Recent discovery has found that the sentinel lymph node (SLN) in the body is the gateway for cancer to spread, which is known as metastasis. The Sentinel Node Oncology Foundation was founded as a non-profit 501 ( c ) ( 3 ) organization in 2003 on the premise that the next level of cancer research and treatment is upon us to understand more about this important gateway, to advance the care and treatment of patients with solid cancer and to help develop new preventative strategies, diagnostics, and patient-specific treatments.

It is now known that the same type of cancer is different from one person to the other. After decades of research, we are poised to enter a new era of medical practice where detailed genetic and other molecular information about a patient’s cancer is routinely used to deploy effective, patient-specific remedies to treat it. We are about to enter the era of precision medicine. (NCI and NIH Precision Medicine Initiative®). The genetic signature of cancer of each patient may be determined so that treatment can be tailored to each cancer patient more precisely and efficiently. This will lead to more precise treatment recommendations, and the avoidance of severe toxic effects from over treatment or treatment working against a particular gene abnormality. The Foundation is building a robust sentinel lymph node databank so that the natural history of patients with solid cancer can be accurately defined by their genetic profiles.